Golestan University of Medical Sciences Repository

Effects of treadmill training on the balance, functional capacity and quality of life in Parkinson's disease: A randomized clinical trial

Arfa-Fatollahkhani, P. and Safar Cherati, A. and Habibi, S.A.H. and Shahidi, G.A. and Sohrabi, A. and Zamani, B. (2020) Effects of treadmill training on the balance, functional capacity and quality of life in Parkinson's disease: A randomized clinical trial. Journal of Complementary and Integrative Medicine, 17 (1).

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There is growing evidence that exercise modalities have considerable effects on Parkinson's disease (PD). This trial aimed to provide a more detailed viewpoint of short-term and long-term treadmill training (TT) effects on some motor and non-motor features of PD. In this prospective, randomized, single-blind clinical trial, 20 mild to moderate PD patients, admitted in Rasoul-e-Akram hospital in Tehran, Iran, were randomly allocated in case (11) and control (9) groups. Treadmill intervention was performed at moderate intensity with 60 of heart rate reserved (HRR) in two 30-min sessions/week for a duration of 10 weeks. Both the groups were evaluated for three times; at the baseline, 2 months later and then 2 months after the second evaluation. We assigned the Timed Up and Go test (TUG), 6-min walk test (6MW), and the SF-8 healthy questionnaire, for assessment of balance, functional capacity, and Quality of life (QoL), respectively. Balance and functional capacity were significantly improved in the case group after the intervention (TUG p-value: 0.003, 6MW p-value: 0.003). Moreover, the long-term analysis revealed significant results as well (TUG p-value: 0.001, 6MW p-value: 0.004). Mental condition's scores of SF-8 in cases were not statistically different in short-term follow-up (F/U). However, analysis illustrated p-value: 0.016 for long-term assessment. The intervention induced significant changes in physical condition's scores in both of the F/Us (PC p-value: 0.013). This study provides evidence that a TT of mild to moderate intensity has significant and persistent benefits for the balance, functional capacity, and QoL in PD. © 2019 2019 Walter de Gruyter GmbH, Berlin/Boston.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: adult; aged; Article; body equilibrium; clinical article; controlled study; disease severity; exercise intensity; female; follow up; functional status; heart rate variability; hospital admission; human; Iran; male; Parkinson disease; prospective study; quality of life; randomized controlled trial; Short Form 8; six minute walk test; therapy effect; timed up and go test; treadmill exercise
Subjects: سیستم عصبی WL
مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 22 Apr 2020 06:24
Last Modified: 22 Apr 2020 06:24
URI: http://eprints.goums.ac.ir/id/eprint/10593

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