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Emerging Theranostic Gold Nanomaterials to Combat Lung Cancer: A Systematic Review

Barabadi, H. and Vahidi, H. and Damavandi Kamali, K. and Hosseini, O. and Mahjoub, M.A. and Rashedi, M. and Jazayeri Shoushtari, F. and Saravanan, M. (2020) Emerging Theranostic Gold Nanomaterials to Combat Lung Cancer: A Systematic Review. Journal of Cluster Science, 31 (2). pp. 323-330.

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Lung cancer remains the significant cause of deaths in males and females worldwide and many attempts have been made for diagnosis and treatment of lung cancer. Nanotechnology has emerged as a novel strategy to design smart nanostructure weapons to combat lung cancer. Recently, the biogenic gold nanoparticles (AuNPs) have attracted highlighted interest for lung cancer theranostics. The current systematic review served to evaluate the anticancer potential of biologically synthesized AuNPs against lung cancer cells through in vitro studies. We provided valuable information regarding the efficacy of biogenic AuNPs suggesting their potential for next generation of anticancer drugs. The articles were identified through international databases involving Cochrane, Web of Science, PubMed, Scopus, Science Direct, ProQuest, and Embase. Eighteen articles were found eligible to enter into the current study. Our findings represented that although some studies reported nontoxicity of biogenic AuNPs against lung cancer cells, most of the studies reported significant anticancer activity of these nanoparticles (NPs) against lung cancer cells. Although the in vitro studies provided preliminary evidence for lung anticancer potential of biogenic AuNPs, further in vivo investigations are required to confirm the efficacy of these NPs through animal models. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.

Item Type: Article
Additional Information: cited By 2
Subjects: سیستم تنفسی WF
QU بیوشیمی
آسیب شناسی QZ
مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 14 Apr 2020 06:51
Last Modified: 14 Apr 2020 06:51
URI: http://eprints.goums.ac.ir/id/eprint/10508

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