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An update and systematic review on the treatment of primary dysmenorrhea

Sharghi, M. and Mansurkhani, S.M. and Ashtary-Larky, D. and Kooti, W. and Niksefat, M. and Firoozbakht, M. and Behzadifar, M. and Azami, M. and Servatyari, K. and Jouybari, L. (2019) An update and systematic review on the treatment of primary dysmenorrhea. Jornal Brasileiro de Reproducao Assistida, 23 (1). pp. 51-57.

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Abstract

Objectives: Primary dysmenorrhea is a painful uterine contraction caused by endometrial laceration. Drug therapies and complementary medicine have been used to treat dysmenorrhea. The aim of this study was to investigate and offer an updated perspective on the treatments for dysmenorrhea. Methods: The present study was conducted in accordance with the PRISMA checklist for systematic reviews and meta-analyses. The required information was collected based on searches for the following keywords: treatment, primary dysmenorrhea, medicinal plants, chemical drugs, and herbs. Searches were performed on databases Pubmed, Web of Sciences, Scopus, Iran medex, and SID by March 2018 to find literature in the English and Persian languages on this subject without a time limit. Results: This review included 17 papers, 10 of which on complementary medicine, three on drug therapies, and four on acupuncture and acupressure. The largest and smallest samples had 303 and 24 patients, respectively. Length of treatment ranged from one to six months and the measures most commonly used in the studies were the visual analogue scale and clinical efficacy. Reported complications included gastrointestinal events, nausea, vomiting, diarrhea, abdominal pain, and liver and kidney disorders. Conclusion: Medicinal plants, drugs, and acupressure seem to suppress pain by reducing the level of prostaglandins, mediating nitric oxide, increasing beta-endorphin levels, blocking the calcium channel, and enhancing circulatory flow through the uterine pathway. Further trials are required to confirm the benefits of the procedures described and ensure the absence of complications. © (Publisher name) (Publishing Year). All Rights Reserved.

Item Type: Article
Additional Information: cited By 2
Uncontrolled Keywords: alpha tocopherol; beta endorphin; celecoxib; diclofenac; essential oil; Foeniculum vulgare extract; ibuprofen; Matricaria chamomilla extract; mefenamic acid; naproxen; sildenafil; Thymus vulgaris extract, abdominal pain; acupressure; acupuncture; Article; diarrhea; drug efficacy; dysmenorrhea; fennel; herb; human; kidney disease; liver disease; Matricaria chamomilla; McGill Pain Questionnaire; medicinal plant; menstruation; multidimensional scaling; nausea; pain severity; Perceived Stress Scale; randomized controlled trial (topic); systematic review; treatment duration; visual analog scale; vomiting; Zataria multiflora
Subjects: بیماریهای زنان WP
فارماکولوژی QV
> دانشکده داروسازی > فارماکولوژی QV

مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Dec 2019 11:02
Last Modified: 18 Dec 2019 11:02
URI: http://eprints.goums.ac.ir/id/eprint/10472

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