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Predicting the in-hospital outcome in acute heart failure: Role of laboratory tests

Torfi, E. and Naderi, N. and Taghavi, S. and Omidi, S. and Amin, A. (2019) Predicting the in-hospital outcome in acute heart failure: Role of laboratory tests. Iranian Heart Journal, 20 (3). pp. 60-65.

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Abstract

Background: Despite impressive advances in therapeutics in the last years, acute heart failure (AHF) remains a major cause of cardiovascular morbidity and mortality. Additionally, worsening renal failure (WRF) during hospitalization has a significant effect on rehospitalization and mortality in such patients. In this study, we aimed to determine the factors impacting on WRF and in-hospital mortality in patients with AHF. Methods: During a 9-month period (September 2016 to May 2017), 104 patients with an episode of AHF (mean age: 75 y) were included in this study. The effects of demographic, echocardiographic, and laboratory findings on WRF and in-hospital outcomes (mortality and urgent heart transplantation) were evaluated retrospectively. Results: Out of the 104 patients, 44.3 developed WRF; the incidence of in-hospital mortality and heart transplantation was 13.4. Among the laboratory parameters, the specific gravity of urine was significantly associated with WRF (P = 0.03), and higher blood uric acid levels (P = 0.01) and lower left ventricular ejection fractions (P = 0.04) were associated with adverse in-hospital outcomes. Additionally, low hemoglobin (P = 0.03), high pro-BNP (P = 0.05), and low left ventricular ejection fractions (P = 0.04) were associated with a prolonged in-hospital stay. Conclusions: Laboratory data can be used upon patient admission to guide the therapy of heart failure in an attempt to reduce WRF and in-hospital stay. © 2019, Iranian Heart Association. All rights reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: amino terminal pro brain natriuretic peptide; bilirubin; hemoglobin; liver enzyme; magnesium; uric acid, acute heart failure; adult; aged; Article; blood cell count; disease exacerbation; echocardiography; heart left ventricle ejection fraction; heart left ventricle size; heart transplantation; hospital mortality; hospitalization; human; incidence; iron binding capacity; kidney failure; laboratory test; length of stay; major clinical study; observational study; prospective study; relative density; retrospective study; sodium blood level; systolic blood pressure; thyroid function; urea nitrogen blood level; urinalysis; very elderly
Subjects: سیستم قلب وعروق WG
پرستاری wy
مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 17 Dec 2019 06:20
Last Modified: 17 Dec 2019 06:20
URI: http://eprints.goums.ac.ir/id/eprint/10422

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