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Emerging Theranostic Silver and Gold Nanomaterials to Combat Prostate Cancer: A Systematic Review

Barabadi, H. and Damavandi Kamali, K. and Jazayeri Shoushtari, F. and Tajani, B. and Mahjoub, M.A. and Alizadeh, A. and Saravanan, M. (2019) Emerging Theranostic Silver and Gold Nanomaterials to Combat Prostate Cancer: A Systematic Review. Journal of Cluster Science, 30 (6). pp. 1375-1382.

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Prostate cancer has emerged as the common malignancy in men and is considered as a global issue. Among different strategies to combat prostate cancer, nanobiotechnology appears as a novel approach for prostate cancer theranostics. The current systematic review discussing the recent development in the prostate anticancer activity of biologically synthesized silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) through laboratory investigations. The databases including Cochrane, Web of Science, PubMed, Scopus, Science Direct, ProQuest, and Embase were used to identify the records. It was found that most of the studies used herbal extracts for preparation of AgNPs and/or AuNPs. Majority of biosynthesized nanoparticles (NPs) were formed with spherical morphology. Besides, all studies reported the size of NPs less than 100 nm. Moreover, PC-3 prostate cancer cell was the predominant cell line that was evaluated for prostate anticancer activity of NPs. In the present study, we provided valuable information suggesting the significant prostate anticancer potential of biogenic AgNPs and/or AuNPs. However, further, in vivo investigations are required to provide stronger evidence of the efficacy of bio-mediated synthesized AgNPs and/or AuNPs to combat prostate cancer. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.

Item Type: Article
Additional Information: cited By 6
Subjects: سیستم ادراری WJ
QU بیوشیمی
آسیب شناسی بالینی QY
مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 10 Dec 2019 06:43
Last Modified: 10 Dec 2019 06:43
URI: http://eprints.goums.ac.ir/id/eprint/10363

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