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First Molecular Diagnosis of Lophomoniasis: the End of a Controversial Story

Fakhar, M. and Nakhaei, M. and Sharifpour, A. and Kalani, H. and Banimostafavi, E.S. and Abedi, S. and Safanavaei, S. and Aliyali, M. (2019) First Molecular Diagnosis of Lophomoniasis: the End of a Controversial Story. Acta Parasitologica, 64 (2). pp. 390-393.

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Abstract

Introduction: We report a case of lophomoniasis in an immunocompetent patient with acute paranasal sinusitis from the north of Iran whose disease was diagnosed by both microscopic and molecular methods. Case Presentation: The patient, a 40-year-old woman, suffered from upper respiratory infection, was referred to the Iranian National Registry Center for Lophomoniasis (INRCL) at the Mazandaran University of Medical Sciences, Sari, Iran, for diagnosis. A direct wet mount of nasal discharge revealed the flagellate protozoa morphologically identified Lophomonas blattarum. Moreover, through a specific polymerase chain reaction (PCR) of nasal discharge, a 214-bp band was observed, confirming the genus Lophomonas spp. The patient was treated successfully with metronidazole 500 mg t.i.d for 1 week. Conclusion: To the best of our knowledge, this is the first molecular detection of lophomoniasis in the literature. According to our preliminary study, a reliable PCR test is available now for detecting the Lophomonas parasite. © 2019, Witold Stefa�ski Institute of Parasitology, Polish Academy of Sciences.

Item Type: Article
Additional Information: cited By 0
Subjects: سیستم گوارشی WI
بیماریهای واگیرWC
انگل شناسی QX
مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 22 Sep 2019 10:47
Last Modified: 22 Sep 2019 10:47
URI: http://eprints.goums.ac.ir/id/eprint/10317

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